To jam and learn the simple chords for Ry Cooder - Little Sister chords, practice playing Eb, Bb and Eb in sequence. I suggest starting at a calm pace of 64 BPM, and as you gain confidence, approach the song's BPM of 129. With Eb Major as the song's key, tweak the capo to cater to your vocal pitch and chord likes.
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Loading chords sheet for Little Sister — Ry Cooder ...